After instilling an ophthalmic drop, how long should punctal pressure be maintained to minimize systemic absorption?

After instilling an ophthalmic drop, how long should punctal pressure be maintained to minimize systemic absorption?

• A. 5 minutes
• B. 1-2 minutes
• C. 30 seconds
• D. 10 seconds

Answer: (B)

When the eye drop is placed, keeping gentle pressure on the puncta helps seal off the drainage pathway, so more of the medication stays in the eye and less reaches the nasal mucosa and the systemic circulation. The recommended duration is about one to two minutes. This time frame allows the drug to be absorbed locally while preventing significant drainage. Pressing for a shorter period may not reduce systemic absorption effectively, and pressing longer doesn’t add much benefit and can be uncomfortable. After removing the pressure, blot any excess tears and proceed with any additional drops if needed, allowing a short interval between drops.

When the eye drop is placed, keeping gentle pressure on the puncta helps seal off the drainage pathway, so more of the medication stays in the eye and less reaches the nasal mucosa and the systemic circulation. The recommended duration is about one to two minutes. This time frame allows the drug to be absorbed locally while preventing significant drainage. Pressing for a shorter period may not reduce systemic absorption effectively, and pressing longer doesn’t add much benefit and can be uncomfortable. After removing the pressure, blot any excess tears and proceed with any additional drops if needed, allowing a short interval between drops.